Once again our heroes are taking a break from saving the galaxy but as we all know, this wouldn’t last long. After watching an episode of Secret Agent Clank, Clank’s new Holo-Vision series, Ratchet stumbles across a news report about Planet Veldin, his home world. The report shows an alien race called Tyhrranoids attacking the once backwater planet and are believed to be working for an evil robot by the name of Dr. Nefarious. Ratchet and Clank leave no time to waste and quickly take off back to the Solana Galaxy to save Veldin. Upon arrival Ratchet is suddenly promoted as the new sergeant for the Galactic Rangers and after clearing out the Tyhrranoid invasion on Veldin the duo are contacted by the President. He informs them that there is one man who has ever fought Nefarious and lived and asks them to find him. Who is this mysterious man? Will he really be able to help stop Nefarious?