I think it practically IS a remake of the first game.
Trying to restart things
PS2 characters are dropped
Brand new galaxy
Brand new story line
Clank has all new abilities
Virtually no reference to any old locations, such as the phoenix and stuff
Old gadget names/designs return
R&C1
Ratchet being a prick to Clank
Short runty little evil villain
R&C2
bolt farming planet formula used
Glider clone
R&C3
Skydiving missions
Tools of Destruction was not afraid to borrow concepts from the games before it. And seeing as how it was the first game of the next generation, it wouldn't be too bad of a thing, seeing as how it's supposed to be self-sustaining, and allow for newcomers to not feel like they are required to have played the PS2 games (Metal Gear!) before playing these.
Well, it's not a totally new galaxy–that's for sure. Plus, VITTI said they were re-making all assests. That doesnt mean that everything is different and totally new-never-before-seen, it just means they using new assets to make returning…anything (EG, the swingshot). Now, Ratchet's wrench may look similar, but I'm sure they still rebuilt it.
"So we fix our eyes not on what is seen, but on what is unseen, since what is seen is temporary, but what is unseen is eternal."